Polycaprolactone · Deep structural injectable · Not reversible

Ellanse Singapore: a collagen-stimulating injectable that cannot be dissolved

Structural support in firm tissue, with a real trade-off.

Ellansé gives some volume at first, then relies on the collagen your body builds around it. Because it cannot be undone, the decision deserves care.

Exam
Before Any Plan
Doctor
Examines You First
Written
Quote After Exam
Orchard
By Appointment

In Brief

Patients in Singapore ask about Ellanse, an injectable of polycaprolactone (PCL) microspheres in gel, placed deep to support firm areas such as the chin or jawline. It may suit people who accept that it cannot be reversed. It does not lift sagging tissue or suit lips.

About This Treatment

Two effects, one after the other

Ellansé, also written Ellanse, is made of polycaprolactone microspheres carried in a carboxymethylcellulose gel. By make-up it is about 30% microspheres, each roughly 25 to 50 µm across, and about 70% gel. It is made by Sinclair.

The gel gives volume on the day. Over the following weeks the gel is absorbed, and fibroblasts lay down collagen around the microspheres that stay behind. That collagen then provides the support over the longer term. So the look on day one is not the final picture. Dosing is planned for what the collagen will do, and results vary.

Because the collagen is what counts, treatment starts with less than the final amount. You are reviewed once the gel has gone and collagen is forming, as that is when the real change can be judged.

How Ellanse treatment is planned in Singapore

Two versions are used. Ellansé-S resorbs sooner and Ellansé-M resorbs later. Both use the same microspheres and carrier. They differ in how long the collagen scaffold persists, and the choice is made for each patient and each area. The product goes deep, on the bone surface or in deep fat compartments where anatomy allows. It is placed in small deposits, never spread as a thin sheet. Slowly, the microspheres break down to carbon dioxide and water. Ellansé is CE-marked as a medical device. It does not have US FDA approval.

Where it may suit

Chin and jawline

Projection at the chin and definition along the jaw, in firm tissue.

Temples and side of the cheek

Hollowed temples and the outer cheek, where structural support is the need.

Backs of the hands

Hands where the tendons have become visible.

The right mindset

People who understand it cannot be reversed and want it for the collagen that follows.

Who should avoid it or wait

Not advised

Known allergy to a component or a history of severe allergic reactions. Bleeding disorders. Non-absorbable filler such as silicone in the area. Earlier filler that has not been mapped.

Postpone

Pregnancy and breastfeeding. Infection or inflammation at or near the site, such as active acne or a cold sore.

Needs assessment first

Autoimmune disease or immune-modifying treatment.

Caution or a change in timing

Blood thinners, a history of keloid or hypertrophic scars, and recent or planned dental work.

What Ellansé cannot do

It cannot be dissolved. Hyaluronidase has no effect on PCL or its gel carrier. If a problem arises it has to be managed, because it cannot be undone. Ellansé does not lift a descended jowl, and for that the doctor may discuss focused ultrasound or the VF Lift. It is not used for lips, tear troughs, or fine lines in thin or mobile skin. If you have never had your face assessed, or you want the option of reversal, a reversible hyaluronic acid filler is usually the gentler place to start. Nor can anyone tell you exactly how long it will last in your face, so no duration should be taken as a prediction.

Side effects and risks

Expected

Swelling, bruising, tenderness at the injection sites, and short-lived firmness where the gel sits.

Specific to firm products

Nodules, and product you can see or feel. These are linked to shallow placement, too much in one spot, or use in mobile areas.

Serious

Vascular complications can happen with any injectable near facial vessels. Read the warning signs so you know when to seek urgent help.

Lumps and earlier filler

A lump should be examined before anyone treats it, usually with ultrasound. Options for nodules include observation, injections, and the Sculpting mode of Time Freeze Laser LCLR. Lumps or heaviness from earlier filler usually call for taking product away, and adding more is not the answer. See our page on pillow face. Ellansé will not be placed over filler that has not been mapped. A lump needs a diagnosis first, because the right response depends on what it is and where it sits.

Recovery, in phases

01
Straight after
Swelling and tenderness, sometimes bruising, with short-lived firmness.
02
That evening
Avoid pressure, heat, alcohol and hard exercise. A cool compress can ease swelling.
03
Next few days
Swelling and bruising settle. Early volume from the gel softens as it integrates.
04
Following months
Collagen forms, so the structural change continues to refine.
05
Follow-up
Treatment is staged. You are reviewed once the gel has gone and collagen is forming. Any unevenness or nodule is checked with ultrasound.

Before you book

01
Share your history
List all earlier fillers or stimulators, with dates and areas if you know them. Declare pregnancy, breastfeeding, autoimmune conditions and keloid history.
02
Report what you take
Mention blood thinners, aspirin, fish oil, or supplements that increase bruising.
03
Prepare your skin
Avoid fresh sun exposure, and pause strong skincare actives as advised.
04
Bring records
Bring past photos and treatment records.

How long it lasts, and how fees work

No duration is promised. How long it holds depends on the version, the area, the amount, your tissue, and any weight change. PCL resorbs over time, and the collagen ages along with the face. Fees are not published. They depend on the areas, the version chosen, the amount your anatomy calls for, staging, and any combined treatment. A written quote comes at consultation, which also decides whether Ellansé is advised at all.

Frequently Asked Questions

It is both, in sequence. The gel gives early volume, then collagen forms around the microspheres and takes over.
No. Hyaluronidase does not act on PCL or its carrier. Problems can only be managed.
The gel is absorbed over weeks. What remains is the collagen response, which differs in shape and amount from the first day.
No. Lips and tear troughs are not areas where Ellansé is used.
Each is a different material. Ellansé is PCL, Radiesse is calcium hydroxylapatite and Sculptra is poly-L-lactic acid. See Sculptra vs Radiesse for more.
Lumps are linked to shallow placement, too much product in one spot, or mobile areas. They should be scanned before treatment.
Usually, yes. Placement is staged, starting with less, and reviewed once collagen is forming. The number of visits is not fixed.
It depends on the areas, the version, the amount needed, staging, and any combined treatment. A written quote comes at consultation.
Mention all earlier fillers or stimulators, pregnancy, breastfeeding, autoimmune conditions, keloid history, blood thinners, aspirin, fish oil and supplements. Bring past photos and records.
SY
Dr Sin Yong
MBBS (NUS) · MRCS (Edinburgh)
MSc Aesthetic Medicine (QMUL) · MSc Practical Dermatology (Cardiff)
Aesthetic physician registered with the Singapore Medical Council.

Check whether Ellansé is right for you

Dr Sin Yong will examine you, explain your options and give any fee in writing.

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References

  1. Schelke LW, et al. Ultrasound-Guided Targeted vs Regional Flooding: A Comparative Study for Improving the Clinical Outcome in Soft Tissue Filler Vascular Adverse Event Management. Aesthet Surg J. 2023;43(1):86-96. View source
  2. Cohen JL, et al. Treatment of Hyaluronic Acid Filler-Induced Impending Necrosis With Hyaluronidase: Consensus Recommendations. Aesthet Surg J. 2015;35(7):844-849. View source
  3. Urso SU, et al. Use of Minimal Amounts of Hyaluronidase in the Ultrasound-Guided Treatment of Acute Vascular Occlusion by Hyaluronic Acid: A Preliminary Report. Aesthet Surg J Open Forum. 2024;6:ojae025. View source
  4. Goodman GJ, et al. A Consensus on Minimizing the Risk of Hyaluronic Acid Embolic Visual Loss and Suggestions for Immediate Bedside Management. Aesthet Surg J. 2020;40(9):1009-1021. View source
  5. Vasconcelos-Berg R, et al. Doppler Ultrasound-Guided Filler Injections: Useful Tips to Integrate Ultrasound in Daily Practice. Aesthet Surg J. 2023;43(7):773-783. View source
  6. Hong GW, et al. Adverse Effects Associated with Dermal Filler Treatments: Part II Vascular Complication. Diagnostics (Basel). 2024;14(14):1555. View source

Studies may involve other devices or protocols, and they do not predict your own result. See our evidence library and editorial policy.

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Last updated 3 November 2026. General information only. Results vary between individuals. Images are illustrative and do not show patients.