Women's health · Evidence guide · Non-device options first

Vaginal laser or radiofrequency: what the evidence says

Two kinds of energy. A mixed set of studies.

Laser and radiofrequency heat tissue in different ways. Neither is a first step, and neither replaces pelvic floor training or standard care for dryness.

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In Brief

Vaginal laser or radiofrequency treatment uses heat to prompt a collagen response in the vaginal wall. Either may be discussed for some women after examination, once non-device options are considered. Trials are mixed, the 2018 FDA caution applies, and neither treats prolapse or pelvic floor weakness.

At a Glance: Vaginal laser or radiofrequency: what the evidence says

What it comparesFractional CO2 laser (G Lift) and monopolar radiofrequency (GF Lift) on Volnewmer.
How they workBoth use heat to prompt a collagen response in the vaginal wall.
First optionsMoisturisers, lubricants and prescribed vaginal oestrogen are considered before any device.
Who should avoid itPregnancy, active infection, undiagnosed bleeding or an abnormal cervical screen under follow-up.
What it cannot doNeither device treats prolapse or pelvic floor weakness.
EvidenceTrials are mixed, and the 2018 FDA caution applies.

What the Research Shows: Vaginal laser or radiofrequency: what the evidence says

  • A 2021 sham-controlled randomised trial of 85 women reported fractional CO2 laser did not significantly improve vaginal symptoms after 12 months; spotting occurred in 30% versus 5% with sham. [1]
  • A 2018 manufacturer-funded post hoc analysis of a sham-controlled trial in 108 premenopausal women reported greater 6-month arousal, lubrication and orgasm score improvement with active radiofrequency than sham. [2]
  • A 2022 meta-analysis of 6 randomised trials with 270 women (4 pooled) found no significant differences between CO2 laser and vaginal estrogen on main measures; non-inferiority was not formally tested. [4]
  • A 2024 sham-controlled randomised trial of 76 women reported greater vaginal laxity improvement at 4, 6 and 12 months, but sexual function improvement not significantly better than sham at all visits. [5]

Figures describe published study groups, which may have used other devices or protocols. They do not predict your result. Updated 3 November 2026.

About This Treatment

The short answer

Neither option can be recommended for every woman, and the research does not settle which one suits whom. Laser tends to be discussed where dryness or thinning is part of the picture. Radiofrequency tends to be discussed for laxity after childbirth. An examination decides. Some women need one, some both, and some neither.

Before either device, it helps to ask whether a simpler step would do. Results vary with both, and a device may not change your symptoms.

Try these before any device

Moisturisers and lubricants

They ease the surface and reduce friction. They do not change lining thickness or laxity.

Prescribed vaginal oestrogen

It supports the lining where low oestrogen drives thinning. It needs a doctor's assessment and prescription, and it does not treat stretched tissue.

Pelvic floor training

It strengthens the muscles that support the bladder, vagina and bowel, ideally guided by a women's health physiotherapist. See our pelvic floor guide.

Vaginal laser or radiofrequency: how they differ

FeatureFractional CO2 laser (G Lift)Monopolar radiofrequency (GF Lift)
Energy10,600 nm laser in a microablative patternElectrical current on the Volnewmer platform
ZonesVaginal lining and openingVaginal canal, opening, outer labia and mons
SurfaceMicro-columns that heal from the tissue between themLeft intact
Often discussed forLaxity with dryness or thinning, often around menopauseLaxity after childbirth; loose outer labia
Evidence in briefMixed; one sham trial found no significant benefit at 12 monthsMixed; results depend on device and measure
Cannot doStrengthen the pelvic floor or correct prolapseStrengthen the pelvic floor or correct prolapse

How each one aims to work

Fractional CO2 laser makes tiny micro-ablative columns in the lining, with heat around them, to prompt collagen remodelling. Radiofrequency heats tissue through electrical resistance, not laser light, and aims at tissue contraction and new collagen over several weeks. With radiofrequency, nothing is injected, implanted or cut. These are aims, not promises. Neither replaces pelvic floor physiotherapy.

The 2018 FDA caution

In 2018 the US Food and Drug Administration warned about energy-based devices marketed for vaginal rejuvenation. It stated it had not evaluated these devices for those uses. It reported cases of vaginal burns, scarring, painful intercourse and chronic pain, and sent notices to seven manufacturers. The same year, the International Society for the Study of Vulvovaginal Disease (ISSVD) and the International Continence Society (ICS) recommended against using laser and radiofrequency for vulvovaginal atrophy. They added that the devices should not be used for lichen sclerosus, vulvodynia, urinary incontinence or rejuvenation outside properly designed clinical trials. In 2021, ACOG stated that laser is neither FDA-approved nor FDA-cleared for symptoms related to menopause, and said more research is needed before recommending it.

What the laser studies found

Sham-controlled trial, JAMA 2021

In 85 women randomised to fractional CO2 laser or sham, laser did not significantly improve vaginal symptoms after 12 months compared with sham.

Review, JAMA Network Open 2022

In six randomised trials with 270 women, CO2 laser was associated with similar improvement in genitourinary symptoms as vaginal oestrogen, with no significant differences on the main measures.

What the radiofrequency studies found

VIVEVE I

In this sham-controlled trial, more women in the active group reported no laxity at six months. A subanalysis of 108 premenopausal women, with authors tied to the manufacturer, found greater six-month improvement in arousal, lubrication and orgasm scores.

VIVEVE II

This later, larger sham-controlled trial did not meet its main sexual function goal at 12 months.

Multipolar radiofrequency, 2024

In 76 women, laxity improved more with active treatment than sham at 4, 6 and 12 months. Sexual function scores did not improve significantly more than sham at all visits.

A note on devices

These trials tested other devices, so they do not prove results for GF Lift.

How to read this evidence

Keep three points in mind. First, a result with one device may not apply to another. Second, a study may show change on one measure and not on another, as the 2024 trial did. Third, some research has manufacturer links, and that should be stated. Most published studies are small, and sham-controlled trials have given mixed results. Our sources do not support a claim that either energy is more effective than the other for laxity. Our evidence library lists more papers.

Who should avoid either device

Both

Pregnancy, active infection, undiagnosed bleeding, an abnormal cervical screen still being followed up, and prolapse or pelvic floor weakness that needs other care first.

After childbirth

Treatment waits until healing is complete.

Radiofrequency

A pacemaker, a defibrillator, or a metal implant near the area.

Laser

Breastfeeding is discussed first. Pelvic mesh or implants and recent pelvic surgery or radiotherapy are assessed individually.

Risks with either device

Warmth or light vibration can be felt during treatment. Mild discharge, spotting, irritation or tenderness can follow laser. Burn, scarring, infection and painful sex can occur, and true rates are unknown, and the FDA reported burns, scarring, painful intercourse and chronic pain with energy devices. The FDA has said these devices carry serious risks and lack adequate evidence for this use. The sham-controlled trial by Li and colleagues used MonaLisa Touch, the laser system used for the G Lift. Report unusual pain, discharge, bleeding or blistering promptly. Fees for GF Lift and G Lift are given in writing after examination, and no treatment stays an option.

Frequently Asked Questions

Neither may be needed. An examination decides, after non-device options are considered, and the evidence does not settle which suits whom.
The evidence is mixed. Some sham-controlled results favour active treatment, while others did not meet their goals. Results vary.
The FDA warned in 2018 that it had not evaluated these devices for vaginal rejuvenation uses.
Not in place of assessment. The ISSVD and ICS said these devices should not be used for urinary incontinence outside properly designed trials.
Not directly. They tested other radiofrequency devices, so they do not prove results for this protocol.
No. A review found similar improvement in symptoms, but they are different treatments, and the sham-controlled picture is mixed.
Some women are advised to have both, some one, and some neither. This depends on your examination.
SY
Dr Sin Yong
MBBS (NUS) · MRCS (Edinburgh)
MSc Aesthetic Medicine (QMUL) · MSc Practical Dermatology (Cardiff)
Aesthetic physician registered with the Singapore Medical Council.

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Dr Sin Yong will examine you, explain your options and give any fee in writing.

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References

  1. Li FG, et al. Effect of Fractional Carbon Dioxide Laser vs Sham Treatment on Symptom Severity in Women With Postmenopausal Vaginal Symptoms: A Randomized Clinical Trial. JAMA. 2021;326(14):1381-1389. View source · DOI · PMID 34636862
  2. Krychman M, et al. Effect of Single-Session, Cryogen-Cooled Monopolar Radiofrequency Therapy on Sexual Function in Women with Vaginal Laxity: The VIVEVE I Trial. J Womens Health (Larchmt). 2018;27(3):297-304. View source · DOI · PMID 29182498
  3. US Food and Drug Administration Statement from FDA Commissioner Scott Gottlieb, M.D., on efforts to safeguard women's health from deceptive health claims and significant risks related to devices marketed for use in medical procedures for "vaginal rejuvenation". FDA statement. 2018. View source
  4. Jang YC, et al. Comparison of Severity of Genitourinary Syndrome of Menopause Symptoms After Carbon Dioxide Laser vs Vaginal Estrogen Therapy: A Systematic Review and Meta-analysis. JAMA Netw Open. 2022;5(9):e2232563. View source · DOI · PMID 36129710
  5. Nappi RE, et al. Efficacy and safety of a device that combines multipolar radiofrequency with pulsed electromagnetic field for the treatment of vulvovaginal atrophy: a randomized, sham-controlled trial. J Sex Med. 2024;21(3):203-210. View source · DOI · PMID 38286753
  6. International Society for the Study of Vulvovaginal Disease, International Continence Society ISSVD/ICS comments on the FDA communication on the use of energy-based devices to perform vaginal 'rejuvenation' or vaginal cosmetic procedures. ISSVD/ICS position statement. 2018. View source
  7. American Urogynecologic Society. Vaginal Energy-Based Devices: AUGS Clinical Consensus Statement. Urogynecology. 2022;28:633-648. View source

Studies may involve other devices or protocols, and they do not predict your own result. See our evidence library and editorial policy.

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Last updated 3 November 2026. General information only. Results vary between individuals. Images are illustrative and do not show patients.